个人简介
冯鹏举，2008年本科毕业于南开大学，2013年于中科院化学研究所获得博士学位，随后在美国纽约州立大学石溪分校化学系工作学习。于2016年加入bet体育365官网网站开始独立研究。主要研究方向为有机光电化学合成方法学开发，含氟功能分子的合成，海洋天然产物合成，生物质资源功能化。至今为止，在Angew. Chem. Int. Ed.，Sci. China. Chem., Chem. Sci.，Green Chemistry等高水平杂志上发表论文40余篇，获中国发明专利授权7项，获得广东省科技进步二等奖（2021，第三完成人），获批广东省珠江人才青年拔尖人才，暨南双百英才等。自独立工作以来在化学合成方向培养或联合培养学硕，均进入其他高校进行博士阶段的深造，包括2016级：马国坚-中山大学；赵俊豪-北京化工大学；2017级未招生；2018级：伍兴-湖南大学；侯力源-香港科技（深圳），宁左州-浙江大学；2019级：周乃富-中国科学院化学所；彭西超-南京大学；2020级：张志成-南开大学
学习经历
2004.09～2008.07 学士 化学 南开大学
2008.09～2013.07 博士 有机化学 中国科学院化学研究所
2013.10～2016.01 博士后研究员 纽约州立大学石溪分校
工作经历
2015.03～至今 副研究员 bet体育365官网网站化学系
研究方向
目前研究主要集中在直接电氧化,简单易操作的实用合成方法学研究.
研究课题
1.含氮杂环合成方法的开发
2.饱和体系及芳香体系含氟冠能团的引进问题
3.具有重要生理活性天然产物的合成，结构改造及活性评估
主要论文
●(49) Electrochemically time-dependent oxidative coupling/coupling-cyclization reaction between heterocycles: tunable synthesis of polycyclic indole derivatives with fluorescence properties. Zuozhou Ning, Zhicheng Zhang, Qingsong Yan, Naifu Zhou, Linzi Wen, Xichao Peng, Yu Tang, Pengju Feng*. Science China Chemistry. 2022, 65, 1962-1967.
●(48) Electrochemically controlled dearomative 2,3-difunctionalization of indoles to synthesize oxoindoline derivatives. Xichao Peng, Linzi Wen, Zuozhou Ning, Zhicheng Zhang, Chengbo Sun, Yu Tang, Pengju Feng*. Organic Chemistry Frontiers. 2022, 9, 3800-3806.
●(47) In vivo genome-wide CRISPR screening identifies ZNF24 as a negative NF-kappaB modulator in lung cancer. Lu Liu, Yuxi Lei, Wensheng Chen, Qian Zhou, Zongyao Zheng, Guandi Zeng, Wanting Liu, Pengju Feng, Zhiyi Zhang, Lei Yu, Liang Chen*, Cell & Bioscience, 2022, 12, 193; Doi.org/ 10.1186/s13578-022-00933-0.
●(46) Tunable alkoxy-nucleophilic addition under photochemical condition: Dioxidation of gem-difluoroalkenes with O2. Yuanwei Liang, Naifu Zhou, Guojian Ma, Linzi Wen, Xing Wu*, Pengju Feng*, Molecular Catalysis, 2022, 528, 112373; Doi.org/ 10.1016/j.mcat.2022.112373.
●(45) Elastic-Electric Coefficient-Sensitive Hydrogel Sensors toward Sweat Detection. Bin shen, Wenjing Peng, Bingtian Su, Lizhen Wu, Zhihao Liu, Huihua Xu, Jiexiu Zhao, Pengju Feng, Fengyu Li*, Analytical Chemistry, 2022, 94, 1910; Doi.org/ 10.1021/acs.analchem.1c05363.
●(44) Thermally Stable, Solvent Resistant, and Multifunctional Thermosetting Polymer Networks with High Mechanical Properties Prepared from Renewable Plant Phenols via Thiol-Ene Photo Click Chemistry. Zirun Lin, Yanzi Ke, Xichao Peng, Xing Wu, Chaoqun Zhang, Hui Zhao*, Pengju Feng* ACS Applied Polymer Materials, 2022, 4, 5330; Doi.org/ 10.1021/acsapm.2c00333.
●(43) F-18- or Lu-177-labeled bivalent ligand of fibroblast activation protein with high tumor uptake and retention. Hongsheng Li, Shimin Ye, Li Li, Jiawei Zhong, Qiongsong Yan, Yuhua Zhong, Pengju Feng, Kongzhen Hu* European Jouranl of Nuclear Medicine and Molecular Imaging, 2022, 49, 2705; Doi.org/ 10.1007/s00259-022-05757-1.
●(42) Radiosynthesis and Preclinical Evaluation of Bispecific PSMA/FAP Heterodimers for Tumor Imaging. Kongzhen Hu, Yong Huang, Shimin Ye, Jiawei Zhong, Qiongsong Yan, Yuhua Zhong, Lilan Fu, Pengju Feng, Hongsheng Li* Pharmaceuticals, 2022, 15, 383; Doi.org/10.3390/ph15030383.
●(41) Electro-oxidative C–H amination of heteroarenes with aniline derivatives via radical–radical cross coupling. Xichao Peng, Junhao Zhao, Guojian Ma, Yan Wu, Shiyu Hu, Zhixiong Ruan*, Pengju Feng*, Green Chemistry, 2021, 23, 8853; Doi.org/10.1039/D1GC02821A.
●(40) Electro-Oxidative Coupling of Azoles with 2- and 3-Haloindoles/Thiophenes Providing Access to 2/3-Halo(Azol-1-Yl)Indoles/Thiophenes. Naifu Zhou, Jianchao Yu, Liyuan Hou, Xing Wu, Zhixiong Ruan*, Pengju Feng*. Advanced Synthesis & Catalysis. 2022, 364, 35-40; doi.org/10.1002/adsc.202100958
●(39) A Diverse Micromorphology of Photonic Crystal Chips for Multianalyte Sensing. Yu Huang, Lingxiao Liu, Xian Yang, Xiaoyu Zhang, Bing Yan, Lei Wu, Pengju Feng, Xiaoding Lou, Fan Xia, Yanling Song, Fengyu Li, Small, 2021, doi.org/10.1002/smll.202006723.
●(38) Electro-Oxidative C–N Bond Formation through Azolation of Indole Derivatives: An Access to 3-Substituent-2-(Azol-1-yl)indoles. Naifu Zhou, Junhao Zhao, Chengbo Sun, Yuqin Lai, Zhixiong Ruan*, Pengju Feng*, Journal of Organic Chemistry. 2021, 86, 16059-16067; doi.org/10.1021/acs.joc.1c01271.
●(37) Direct Electrochemical Synthesis of Sulfur-Containing Triazolium Inner Salts. Yueheng Li, Zhixing Huang, Guangquan Mo, Wei Jiang, Chengwei Zheng, Pengju Feng*, Zhixiong Ruan*, Chinese Journa of Chemistry. 2021, 39, 942-946.
●(36) Novel 18F-Labeled Isonicotinamide-Based Radioligands for Positron Emission Tomography Imaging of Glycogen Synthase Kinase-3β. Yuhua Zhong, Shaoxi Yang, Jianyu Cui, Jie Wang, Lin Li, Yilin Chen, Junjie Chen, Pengju Feng, Shun Huang, Hongsheng Li, Yanjian Han, Ganghua Tang, Kongzhen Hu*, Mol. Pharmacetics, 2021, 18, 1277-1284.
●(35) Rapid self-healing, multiple recyclability and mechanically robust plant oil-based epoxy resins enabled by incorporating tri-dynamic covalent bonding. Chaoqun Zhang*, Xiao Wang, Dunsheng Liang, Henghui Deng, Zirun Lin, Pengju Feng*, Qinwen Wang*. Journal of Materials Chemistry A 2021, 9, 18431-18439.
●(34) Late-stage azolation of benzylic C‒H bonds enabled by electrooxidation. Zhixiong Ruan*, Zhixing Huang, Zhongnan Xu, Shaogao Zeng, Pengju Feng*, Peng-Hua Sun*. Science China Chemistry 2021, 64, 800-807.
●(33) Consequent Construction of C–C and C–N Bonds via Palladium-Catalyzed Dual C–H Activation: Synthesis of Benzo[c]cinnoline Derivatives. Hongsheng Li, Junhao Zhao, Songjian Yi, Kongzhen Hu, Pengju Feng*, Organometallics 2021, 40, 880-889.
●(32) Continuous-Flow Electrochemistry Promoted Aza-Wacker Cyclizations. Xichao Peng, Pengju Feng* Chinese Journal of Organic Chemistry, 2021, 41, 2918-2919.
●(31) An Easy Access to Pyrogallol Derivatives Using a Practical Auxiliary, Xing Wu, Songjian Yi, Yifeng Huang, Ling Lin, Yu Tang*, Pengju Feng*, ChemistrySelect 2021, 6, 538-541..
●(30) Photoredox initiated azole-nucleophilic addition: oxo-azolation of gem-difluoroalkenes
Xing Wu, Guojian Ma, Xichao Peng, Zuozhou Ning, Zirun Lin, Xiaoguang Chen, Yu Tang*, Pengju Feng*. Organic Chemistry Frontiers. 2021, 8, 4817-4877.
●(29) Photodriven Regeneration of G-Quadruplex Aptasensor for Sensitively Detecting Thrombin. Liangliang Zhang, Xiaoyu Zhang, Pengju Feng, Qi Han, Wei Liu, Ying Lu*, Chunxia Song, Fengyu Li* Analytical chemistry 2020, 92, 7419-7424..
●(28) Renewable Castor Oil based Waterborne Polyurethane Networks: Simultaneously Showing High Strength, Self-healing, Processability and Tunable Multi-shape Memory. Chaoqun Zhang*, Haiyan Liang, Dunsheng Liang, Zirun Lin, Qian Chen, Pengju Feng*, Qinwen Wang, Angew. Chem. Int. Ed. 2021, 60, 4289-4299..
●(27) The investigation and bioorthogonal anticancer activity enhancement of a triphenylphosphine-labile prodrug of seleno-combretastatin-4. Liyuan Hou, Wei Huang, Jiaqi Cheng, Xuanru Deng, Haoqiang Lai, Zhen Chen, Zepang Zhan, Pengju Feng*, Yiqun Li*, Fang Yang*, Tianfeng Chen. Chem. Commun. 2020, 56, 14495-14498..
●(26) A cysteine derivative-enabled ultrafast thiol-ene reaction for scalable synthesis of a fully bio-based internal emulsifier for high-toughness waterborne polyurethanes. Xiao Wang, Haiyan Liang, Jizhou Jiang, Qingwen Wang, Ying Luo, Pengju Feng*, Chaoqun Zhang*. Green Chem. 2020, 22, 5722.
●(25) Adjusting lipid-water distribution coefficient of Iridium (III) complexes for enhancing its cellular penetration and treatment efficacy to antagonize cisplatin resistance in cervical cancer Wei Huang, Zhen Chen, Liyuan Hou, Pengju Feng*, Yiqun Li*, Tianfeng Chen, Dalton Transactions 2020, 49, 11556-11564.
●(24) Facile One-pot Protocol of Derivatization Nitropyridines: Access to 3-Acetamidopyridin-2-yl 4-methylbenzenesulfonate Derivatives Ling, Lin, Xiaoguang Chen, Junhao Zhao, Suitao Lin, Guojian Ma, Xiaojian Liao*, Pengju Feng*, Heterocycl. Commun 2019, 25, 138-145;
●(23) Tailoring the Performance of Vegetable Oil-Based Waterborne Polyurethanes through Incorporation of Rigid Cyclic Rings into Soft Polymer Networks Haiyan, Liang, Yanchun Li, Siying Huang, Kaixi Huang, Xueyi Zeng, Qianwen Dong, Chengguo Liu, Pengju Feng*, Chaoqun zhang*, ACS Sustainable Chem. Eng 2020, 8, 914-925.
●(22) Total Synthesis of Thermoactinoamide A and its Analogue Yueguang Sun, Hang-bin Li, Rong Zhou, Hailin Wang, Pengju Feng*, Shihai Xu*, Heterocycles 2019, 98, 789-497.
●(21) Simple Aggregation-Induced Emission-Based Multifunctional Fluorescent Dots for Cancer Therapy in Vitro. Xueran Lin, Junhao Zhao, Wei Huang, Hongxing Liu, Pengju Feng*,Fang Yang*, Tianfeng Chen. Chemistry an asian journal 2019, 14, 4160-4163.
●(20) Electro-oxidative and Regioselective C-H Azolation of Phenol and Aniline Drivatives. Pengju Feng#*, Guojian Ma#, Xiaoguang Chen, Xing Wu, Ling Lin, Peng Liu, Tianfeng Chen*. Angew. Chem. Int. Ed. 2019, 131, 8488-8492.
●(19) One-pot Protocol to Synthesize 2-Aminophenols from Anilines via Palladium-catalyzed C-H Acetoxylation. Junhao Zhao, Yifeng Huang, Guojian Ma, Ling Lin, Pengju Feng*. Organometallics 2019, 38, 2084-2091.
●(18) 实用导向基辅助下的邻苯二酚衍生物便捷合成（Facile Synthesis of Pyrocatechol Derivatives Using a Practical Auxiliary） 林玲#，林学然#，冯鹏举*；合成化学 （HECHENG HUAXUE）2019, 9..
●(17) 高校化学实验队伍中存在的问题及建议。 林玲，冯鹏举；广州化学，2019， 11期
●(16) Synthesis and Biological Evaluation of Reniochalistatins A–E and a Reniochalistatin E Analogue. Rong Zhou,Yueguang sun,Hangbin Li, Weili Long, Xiaojian Liao, Pengju Feng*, Shihai Xu*. ChemMedChem 2018, 13, 2202-2207.
●(15) Copper‐Catalyzed Direct C−H Bond Arylation of Benzoxazoles with Anilines. Pengju Feng, Guojian Ma, Tianyu Zhang, Changwei Wang* Asian Journal of Organic Chemistry. 2018, 7, 788-792.
●(14) Isolation and Synthesis of Misszrtine A: A Novel Indole Alkaloid From Marine Sponge-Associated Aspergillus sp. SCSIO XWS03F03 Rong Zhou, Xiaojian Liao, Hangbin Li, Jing Li, Pengju, Feng*, Bingxin Zhao*, Shihai Xu*. Front. Chem. 2018, 6, 212.
●(13) Cancer-targeted design of bioresponsive prodrug with enhanced cellular uptake to achieve precise cancer therapy Yuanwei Liang, Wei Huang, Delong Zeng, Xiaoting Huang, Leung Chan, Chaoming Mei, Pengju, Feng; Choon-Hong Tan; Tianfeng Chen*. Drug delivery. 2018, 25, 1350-1361.
●(12) Selenadiazole Derivatives Inhibit Angiogenesis-Mediated Human Breast Tumor Growth by Suppressing the VEGFR2‐Mediated ERK and AKT Signaling Pathways Haoqiang Lao, Xiaoyan Fu, Chengcheng Sang, Liyuan Hou, Pengju, Feng, Xiaoling Li, Tianfeng Chen*. Chemistry an asian journal 2018, 13, 1447-1457.
●(11) Optically Probing the Localized to Delocalized Transition in the Mo2-Mo2Mixed-valence Systems. Yi Yang Wu#, Miao Meng#, Gang Yi Wang, Pengju Feng and Chun Y. Liu*. Chem. Commun., 2017, 53,3030-3033.
●(10) Enhancement of Antiangiogenic Efficacy of Iron(II) Complex by Selenium Substitution. Haoqiang Lai, Xiang Zhang, Pengju, Feng，Lina Xie, Jinjin Chen, Tianfeng Chen*. Chemistry an asian journal 2017, 12, 982-987.
●(9) Access to a New Class of Synthetic Building Blocks via Trifluoromethoxylation of Pyridines and Pyrimidines. Pengju, Feng;‡ Hojczyk, K.;‡ Chenbo, zhang; Ming-Yu, Ngai*. Chem. science 2016, 7, 424-429. (‡ equal contribution) (IF = 9.21) (highlighted in OPR&D)
●(8) Trifluoromethoxylation of Arenes: Synthesis of Ortho-Trifluoromethoxylated Aniline Derivatives via OCF3-Migration. Hojczyk, K.;‡ Pengju, Feng;‡ Chenbo, zhang; Ming-Yu, Ngai*. Angew. Chem. Int.. Ed. 2014, 53, 14559-14563. (‡ equal contribution) (IF = 11.26) (reviewed in synlett)
●(7) An Approach to the Hexacyclic Skeleton of Trigonoliimines. Pengju, Feng; Yukai, Fan; Fazhen, Xue.; Weigang, Liu.; Songlei, Li.; Yian, Shi*. Org. Lett. 2011, 13, 5827-5829. (IF = 6.36)
●(6) Facile Synthesis of 4-Methyl-5-hexyl- -butyrolactone via Nef Reaction as a Key Step. Zhi Li; Changwei Wang; Pengju Feng*. (* corresponding author) Helv. Chim. Acta. 2015, 98, 795-799. (IF = 1.14)
●(5) Protocol for the Synthesis of ortho-Trifluoromethoxylated Aniline Derivatives. Pengju, Feng; Ming-Yu, Ngai*. J. Vis. Exp. (accept) (IF = 1.33)
●(4) A Concise Approach to the Dalescnol Skeleton. Yukai, Fan.; Pengju, Feng.; Mao, Liu.; Hongjie, Pan.; Yian, Shi*. Organic Letters 2011, 13, 4494-4497. (IF = 6.36)
●(3) Stereoselective construction of the tetracyclic core of Cryptotrione. Song, Chen.; Chao, Rong.; Pengju, Feng.; Songlei, Li.; Yian, Shi*. Org. Biomol. Chem. 2012, 10, 5518-5520. (IF = 3.56)
●(2) An Approach to the Skeleton of Aspidophylline A. Qi Li, Guang Li, Shaobo Ma, Pengju Feng, and Yian Shi*. Org. Lett. 2013, 15, 2601-2603. (IF = 6.36)
●(1) A Concise Approach to the spiroaminal Fragment of Marineosins. Guang Li, Xun Zhang, Qi Li, Pengju Feng, and Yian Shi*. Org. Biomol. Chem. 2013, 11, 2936-2938. (IF = 3.56)
讲授课程
《有机化学》、《有机合成》、《高等有机化学》、《有机化学实验》
承担课题
●国家自然科学基金青年科学基金项目：新型三氟甲氧基试剂的合成与应用，（2017/01–2019/12，20万，21602078），项目主持人；
●广东省普通高校特色创新类项目：三氟甲氧基化反应的开发及应用于硒二唑类化合物的性能优化，（编号2017KTSCX011，2017.12-2019.12）， 项目主持人
●bet体育365官网网站科研培育与创新基金跃升计划：三氟甲氧基化反应的开发及应用于硒二唑类化合物的性能优化，，(2017/01–2018/12，12万，11617432)，项目主持人。
●广东省基础与应用基础研究基金项目 面上项目：电化学条件下芳胺及芳香醚衍生物的绿色合成反应开发，(2019/10–2022/9，10万，2019A1515011743)，项目主持人。
●广东省基础与应用基础研究基金项目 面上项目：电化学经济实用构筑多样性C-F键方法探索，(2023/1–2025/12，10万，2023A1515012251)，项目主持人
荣誉与奖励
●bet体育365官网网站新任教师教学竞赛二等奖2017
● 广东省珠江人才计划—青年拔尖人才 2017
●广东省科学技术进步二等奖奖（2021）植物油基环保木器漆涂料制作关键技术及应用
●中国商业联合会科学技术奖商业科技进步二等奖 （2021） 植物油基木器涂料制备关键技术及应用
●中国产学研促进会产学研合作创新奖二等奖（2021）植物油基水性木器涂料制备关键制备技术创新与产业化
●第二届全国大学生化学创新实验竞赛全国赛一等奖（2021）一锅三步由硝基芳烃合成邻氨基酚衍生物
●第二届全国大学生化学创新实验竞赛华南赛区一等奖（2021）苯酚衍生物的电化学选择性C-H唑胺化反应研
●第三届全国大学生化学创新实验竞赛全国赛一等奖（2022）反应时间调控的电化学吲哚氧化偶联/偶联环化反应研究
社会职务
《合成化学》编委
广东省药学会第一届核药学专业委员会常务委员
